Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model.

作者: Adib Zendedel , Sonja Johann , Soraya Mehrabi , Mohammad-taghi Joghataei , Gholamreza Hassanzadeh

DOI: 10.1007/S12035-015-9203-5

关键词:

摘要: … -1a treatment shifts the microglia phenotype within the spinal cord lesion site from a M1 to a M2 protective microglia cell, we also propose that SDF-1a protect neurons from cell death by …

参考文章(50)
Lili Cui, Huiling Qu, Ting Xiao, Mei Zhao, Jukka Jolkkonen, Chuansheng Zhao, Stromal cell-derived factor-1 and its receptor CXCR4 in adult neurogenesis after cerebral ischemia Restorative Neurology and Neuroscience. ,vol. 31, pp. 239- 251 ,(2013) , 10.3233/RNN-120271
Martin M Mortazavi, Ketan Verma, Olivia A Harmon, Christoph J Griessenauer, Nimer Adeeb, Nicholas Theodore, R Shane Tubbs, None, The microanatomy of spinal cord injury: A review Clinical Anatomy. ,vol. 28, pp. 27- 36 ,(2015) , 10.1002/CA.22432
Ruben Orihuela, Christopher A McPherson, Gaylia Jean Harry, Microglial M1/M2 polarization and metabolic states British Journal of Pharmacology. ,vol. 173, pp. 649- 665 ,(2016) , 10.1111/BPH.13139
Kristina A. Kigerl, Phillip G. Popovich, Toll-like receptors in spinal cord injury. Current Topics in Microbiology and Immunology. ,vol. 336, pp. 121- 136 ,(2009) , 10.1007/978-3-642-00549-7_7
J. P. de Rivero Vaccari, G. Lotocki, A. E. Marcillo, W. D. Dietrich, R. W. Keane, A Molecular Platform in Neurons Regulates Inflammation after Spinal Cord Injury The Journal of Neuroscience. ,vol. 28, pp. 3404- 3414 ,(2008) , 10.1523/JNEUROSCI.0157-08.2008
Takashi Nagasawa, CXC chemokine ligand 12 (CXCL12) and its receptor CXCR4. Journal of Molecular Medicine. ,vol. 92, pp. 433- 439 ,(2014) , 10.1007/S00109-014-1123-8
V Pétrilli, S Papin, C Dostert, A Mayor, F Martinon, J Tschopp, Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death & Differentiation. ,vol. 14, pp. 1583- 1589 ,(2007) , 10.1038/SJ.CDD.4402195
John G. Walsh, Daniel A. Muruve, Christopher Power, Inflammasomes in the CNS Nature Reviews Neuroscience. ,vol. 15, pp. 84- 97 ,(2014) , 10.1038/NRN3638
Woei-Cherng Shyu, Shinn-Zong Lin, Pao-Sheng Yen, Ching-Yuan Su, Der-Cherng Chen, Hsiao-Jung Wang, Hung Li, Stromal Cell-Derived Factor-1α Promotes Neuroprotection, Angiogenesis, and Mobilization/Homing of Bone Marrow-Derived Cells in Stroke Rats Journal of Pharmacology and Experimental Therapeutics. ,vol. 324, pp. 834- 849 ,(2008) , 10.1124/JPET.107.127746
M. Lu, E. A. Grove, R. J. Miller, Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor Proceedings of the National Academy of Sciences of the United States of America. ,vol. 99, pp. 7090- 7095 ,(2002) , 10.1073/PNAS.092013799