Safety and performance of cohesive polydensified matrix hyaluronic acid fillers with lidocaine in the clinical setting - an open-label, multicenter study.

摘要: Cohesive polydensified matrix (CPM®) hyaluronic acid fillers are now available with or without lidocaine. The aim of this study was to investigate the safety and performance CPM® lidocaine in clinical setting. In an open-label, prospective, postmarketing study, 108 patients from seven sites Germany Denmark were treated one more lidocaine-containing fillers. Performance assessed using Merz Aesthetics Scales® (MAS). Pain rated on 11-point visual analog scale. Patients' physicians' satisfaction as well adverse events recorded. Improvements ≥1-point MAS immediately after 17 days posttreatment observed ~90% compared baseline. All investigators ejection force, product positioning, similar superior respective nonlidocaine products. Overall, 94% satisfied esthetic outcomes willing continue except results, all repeat treatment. Mean pain scores low during (<3.0) injection (<0.6). Except for case bruising, mild moderate. safe effective a wide range facial indications.