Aging-dependent changes in the radiation response of the adult rat brain.

作者: Matthew K Schindler , M Elizabeth Forbes , Mike E Robbins , David R Riddle

DOI: 10.1016/J.IJROBP.2007.10.054

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摘要: PURPOSE: To assess the impact of aging on the radiation response in the adult rat brain. METHODS AND MATERIALS: Male rats 8, 18, or 28 months of age received a single 10-Gy …

参考文章(63)
Rolf-Dieter Kortmann, Beate Timmermann, Roger E. Taylor, Giovanni Scarzello, Ludwig Plasswilm, Frank Paulsen, Branislav Jeremic, Astrid K. Gnekow, Karin Dieckmann, Sylvia Kay, Michael Bamberg, Current and future strategies in radiotherapy of childhood low-grade glioma of the brain. Part II: Treatment-related late toxicity. Strahlentherapie Und Onkologie. ,vol. 179, pp. 585- 597 ,(2003) , 10.1007/S00066-003-8104-0
C. D. Dijkstra, E. A. Dopp, D. Chao, W. Calame, G. G. Macpherson, J. G. M. C. Damoiseaux, Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1. Immunology. ,vol. 83, pp. 140- 147 ,(1994)
Terrence Town, Veljko Nikolic, Jun Tan, The microglial "activation" continuum: from innate to adaptive responses Journal of Neuroinflammation. ,vol. 2, pp. 24- 24 ,(2005) , 10.1186/1742-2094-2-24
S Elkabes, EM DiCicco-Bloom, IB Black, Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function The Journal of Neuroscience. ,vol. 16, pp. 2508- 2521 ,(1996) , 10.1523/JNEUROSCI.16-08-02508.1996
Nikki J. Holbrook, Thomas E. Johnson, Edward L. Schneider, John H. Morrison, John W. Rowe, Handbook of the Biology of Aging ,(1990)
Yang Fan, Zhengyan Liu, Philip R. Weinstein, John R. Fike, Jialing Liu, Environmental enrichment enhances neurogenesis and improves functional outcome after cranial irradiation European Journal of Neuroscience. ,vol. 25, pp. 38- 46 ,(2007) , 10.1111/J.1460-9568.2006.05269.X
A. Jemal, R. Siegel, E. Ward, T. Murray, J. Xu, M. J. Thun, Cancer statistics, 2007. CA: A Cancer Journal for Clinicians. ,vol. 57, pp. 43- 66 ,(2007) , 10.3322/CANJCLIN.57.1.43
Stephanos Kyrkanides, M.Kerry O'Banion, Phyllis E Whiteley, JoAnne C Daeschner, John A Olschowka, Enhanced glial activation and expression of specific CNS inflammation-related molecules in aged versus young rats following cortical stab injury. Journal of Neuroimmunology. ,vol. 119, pp. 269- 277 ,(2001) , 10.1016/S0165-5728(01)00404-0