Pathogenesis of presbycusis in animal models: a review.
作者： Anna R. Fetoni , Pasqualina M. Picciotti , Gaetano Paludetti , Diana Troiani
DOI: 10.1016/J.EXGER.2010.12.003
关键词:
摘要: Abstract Presbycusis is the most common cause of hearing loss in aged subjects, reducing individual's communicative skills. Age related can be defined as a progressive, bilateral, symmetrical due to age degeneration and it considered multifactorial complex disorder, with both environmental genetic factors contributing aetiology disease. The decline sensitivity caused by ageing damage at different levels auditory system (central peripheral). Histologically, cochlea shows stria vascularis, sensorineural epithelium, neurons central pathways. mechanisms responsible for age-associated are still incompletely characterized. This work aims give broad overview scientific findings presbycusis, focusing mainly on experimental studies animal models.
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