Nitrones and Oxaziridines. XLV. Formation of Pyrrolo[1,2-a]indoles by Intramolecular Nitrone Cycloaddition

摘要: The N-allylindole-2-carbaldehydes (5)-(8) and related methyl ketones (9)-(12) undergo reaction with N- methylhydroxylamine to give the cycloadducts (14)-(17) (19)-(22), respectively. These adducts contain isoxazolidine rings fused pyrrolo [1,2-a] indole systems. Corresponding cycloaddition of propargylindole derivatives (24) (25) could not be effected nitrone (26) was isolated. underwent hydrogenolysis N-O bond amino alcohols (27)-(30), together traces (31)-(34). X-Ray crystallographic data for (15) (16b) are presented.