Six-Membered Ring Systems: Diazines and Benzo Derivatives

Feng-Cheng Jia, Cheng Xu, Zhi-Wen Zhou, Qun Cai, Deng-Kui Li, An-Xin Wu, Consecutive Cycloaddition/SNAr/Reduction/Cyclization/Oxidation Sequences: A Copper-Catalyzed Multicomponent Synthesis of Fused N-Heterocycles Organic Letters. ,vol. 17, pp. 2820- 2823 ,(2015) , 10.1021/ACS.ORGLETT.5B01242

Philip N. Collier, David Messersmith, Arnaud Le Tiran, Upul K. Bandarage, Christina Boucher, Jon Come, Kevin M. Cottrell, Veronique Damagnez, John D. Doran, James P. Griffith, Suvarna Khare-Pandit, Elaine B. Krueger, Mark W. Ledeboer, Brian Ledford, Yusheng Liao, Sudipta Mahajan, Cameron S. Moody, Setu Roday, Tiansheng Wang, Jinwang Xu, Alex M. Aronov, Discovery of Highly Isoform Selective Thiazolopiperidine Inhibitors of Phosphoinositide 3-Kinase γ Journal of Medicinal Chemistry. ,vol. 58, pp. 5684- 5688 ,(2015) , 10.1021/ACS.JMEDCHEM.5B00498

Marcel Mirel Popa, Emilian Georgescu, Mino R Caira, Florentina Georgescu, Constantin Draghici, Raluca Stan, Calin Deleanu, Florea Dumitrascu, Indolizines and pyrrolo[1,2-c]pyrimidines decorated with a pyrimidine and a pyridine unit respectively. Beilstein Journal of Organic Chemistry. ,vol. 11, pp. 1079- 1088 ,(2015) , 10.3762/BJOC.11.121

Mohammed Afzal Azam, Janarthanan Thathan, Selvaraj Jubie, None, Dual targeting DNA gyrase B (GyrB) and topoisomerse IV (ParE) inhibitors: A review. Bioorganic Chemistry. ,vol. 62, pp. 41- 63 ,(2015) , 10.1016/J.BIOORG.2015.07.004

Lara Bianchi, Alessandro Carloni-Garaventa, Massimo Maccagno, Marcella Pani, Giovanni Petrillo, Carlo Scapolla, Cinzia Tavani, Synthesis of poly-functionalized pyrazoles and pyridazines from nitrobutadienes: an interesting dichotomy of practical relevance Tetrahedron. ,vol. 71, pp. 7550- 7561 ,(2015) , 10.1016/J.TET.2015.08.014

Raphaël Rahmani, Kung Ban, Amy J. Jones, Lori Ferrins, Danny Ganame, Melissa L. Sykes, Vicky M. Avery, Karen L. White, Eileen Ryan, Marcel Kaiser, Susan A. Charman, Jonathan B. Baell, 6-Arylpyrazine-2-carboxamides : a new core for Trypanosoma brucei inhibitors Journal of Medicinal Chemistry. ,vol. 58, pp. 6753- 6765 ,(2015) , 10.1021/ACS.JMEDCHEM.5B00438

Jianming Yan, Guan Liang Tay, Cuien Neo, Bo Ra Lee, Philip Wai Hong Chan, Gold-Catalyzed Cycloisomerization and Diels–Alder Reaction of 1,6-Diyne Esters with Alkenes and Diazenes to Hydronaphthalenes and -cinnolines Organic Letters. ,vol. 17, pp. 4176- 4179 ,(2015) , 10.1021/ACS.ORGLETT.5B01935

Mansi Garg, Monika Chauhan, Pankaj Kumar Singh, Jimi Marin Alex, Raj Kumar, Pyrazoloquinazolines: Synthetic strategies and bioactivities. European Journal of Medicinal Chemistry. ,vol. 97, pp. 444- 461 ,(2015) , 10.1016/J.EJMECH.2014.11.051

Karuppusamy Sakthivel, Kannupal Srinivasan, Iodine/Water‐Mediated Oxidation of o‐Alkynylaroyl Compounds and Application of the Products of Oxidation in the Synthesis of Nitrogen Heterocycles European Journal of Organic Chemistry. ,vol. 2013, pp. 3386- 3396 ,(2013) , 10.1002/EJOC.201300046

Jongwon Lim, Michael D. Altman, James Baker, Jason D. Brubaker, Hongmin Chen, Yiping Chen, Melanie A. Kleinschek, Chaomin Li, Duan Liu, John K.F. Maclean, Erin F. Mulrooney, Jeremy Presland, Larissa Rakhilina, Graham F. Smith, Ruojing Yang, Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications Bioorganic & Medicinal Chemistry Letters. ,vol. 25, pp. 5384- 5388 ,(2015) , 10.1016/J.BMCL.2015.09.028