A mixed methods randomised feasibility trial investigating the management of benign paroxysmal positional vertigo in acute traumatic brain injury.

摘要: Traumatic brain injury (TBI) is the leading cause of long-term disability in working age adults. Recent studies show that most acute TBI patients demonstrate vestibular features dizziness and imbalance, often from combined peripheral central dysfunction. Effective treatment for impairments post-TBI important given its significant adverse impact upon quality life employment prospects. The frequent disorder benign paroxysmal positional vertigo (BPPV), affecting approximately half cases. Although there effective idiopathic BPPV, are no high-quality clinical data BPPV regarding prevalence, natural history, which when best time to treat. In particular, observational suggest may be recurrent, indicating hyperacute futile. Given potential hurdles lack accurate data, current study was designed provide information feasibility optimal design future large-scale prospective would compare different interventions their timing BPPV. A multi-centre randomised mixed methods employed. We aim recruit 75 across a range severities, three major trauma centres London. Patients will one arms: (1) therapist-led manoeuvres, (2) patient-led exercises (3) advice. Participants re-assessed by blinded outcome assessors at 4 12 weeks. Acceptability intervention obtained patient interviews end therapist study. Primary outcomes relate parameters including recruitment retention rates, events fidelity. also more estimate prevalence cases on ward. nature our inform trial TBI. Important we obtain this study, key designing include estimating admitted UK wards, elucidating both care-provider barriers delivering treatment. ISRCTN, ISRCTN91943864 . Registered 10 February 2020.