Regulation of neuronal communication by G protein-coupled receptors
作者： Yunhong Huang , Amantha Thathiah
DOI: 10.1016/J.FEBSLET.2015.05.007
关键词:
摘要: Neuronal communication plays an essential role in the propagation of information brain and requires a precisely orchestrated connectivity between neurons. Synaptic transmission is mechanism through which neurons communicate with each other. It strictly regulated process involves membrane depolarization, cellular exocytosis machinery, neurotransmitter release from synaptic vesicles into cleft, interaction ion channels, G protein-coupled receptors (GPCRs), downstream effector molecules. The focus this review to explore GPCRs protein-signaling neurotransmission, highlight function GPCRs, are localized both presynaptic postsynaptic terminals, regulation intrasynaptic intersynaptic communication, discuss involvement astrocytic neuronal communication.
core.ac.uk
elsevier.com
sci-hub.se 参考文章(211)
L. Mrzljak, A. I. Levey, P. S. Goldman-Rakic, Association of m1 and m2 muscarinic receptor proteins with asymmetric synapses in the primate cerebral cortex: morphological evidence for cholinergic modulation of excitatory neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 90, pp. 5194- 5198 ,(1993) , 10.1073/PNAS.90.11.5194
Maria R Domenici, Shahnaz C Azad, Giovanni Marsicano, Anja Schierloh, Carsten T Wotjak, Hans-Ulrich Dodt, Walter Zieglgänsberger, Beat Lutz, Gerhard Rammes, Cannabinoid Receptor Type 1 Located on Presynaptic Terminals of Principal Neurons in the Forebrain Controls Glutamatergic Synaptic Transmission The Journal of Neuroscience. ,vol. 26, pp. 5794- 5799 ,(2006) , 10.1523/JNEUROSCI.0372-06.2006
C.G. Reich, G.R. Mihalik, A.N. Iskander, J.C. Seckler, M.S. Weiss, Adolescent chronic mild stress alters hippocampal CB1 receptor-mediated excitatory neurotransmission and plasticity Neuroscience. ,vol. 253, pp. 444- 454 ,(2013) , 10.1016/J.NEUROSCIENCE.2013.08.066
C. J. Dubois, P. Ramamoorthy, M. D. Whim, S. J. Liu, Activation of NPY type 5 receptors induces a long-lasting increase in spontaneous GABA release from cerebellar inhibitory interneurons Journal of Neurophysiology. ,vol. 107, pp. 1655- 1665 ,(2012) , 10.1152/JN.00755.2011
Masanobu Kano, Kouichi Hashimoto, Mariko Miyata, Masahiko Watanabe, Roles of Phospholipase Cβ4 in Synapse Elimination and Plasticity in Developing and Mature Cerebellum Molecular Neurobiology. ,vol. 23, pp. 69- 82 ,(2001) , 10.1385/MN:23:1:69
Catherine Léon, Béatrice Hechler, Catherine Vial, Claude Leray, Jean-Pierre Cazenave, Christian Gachet, The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells FEBS Letters. ,vol. 403, pp. 26- 30 ,(1997) , 10.1016/S0014-5793(97)00022-7
Amantha Thathiah, Bart De Strooper, The role of G protein-coupled receptors in the pathology of Alzheimer's disease. Nature Reviews Neuroscience. ,vol. 12, pp. 73- 87 ,(2011) , 10.1038/NRN2977
Kiyoyuki Kitaichi, Takafumi Hori, Lalit K Srivastava, Rémi Quirion, Antisense oligodeoxynucleotides against the muscarinic m2, but not m4, receptor supports its role as autoreceptors in the rat hippocampus Molecular Brain Research. ,vol. 67, pp. 98- 106 ,(1999) , 10.1016/S0169-328X(99)00047-9
E T Tzavara, F P Bymaster, C C Felder, M Wade, J Gomeza, J Wess, D L McKinzie, G G Nomikos, Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice. Molecular Psychiatry. ,vol. 8, pp. 673- 679 ,(2003) , 10.1038/SJ.MP.4001270
Arthur Konnerth, Jörg Dreessen, George J Augustine, None, Brief dendritic calcium signals initiate long-lasting synaptic depression in cerebellar Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 89, pp. 7051- 7055 ,(1992) , 10.1073/PNAS.89.15.7051