Coarse-grained modeling of interactions of lipid bilayers with supports.

摘要: We characterize the differences between supported and unsupported lipid bilayer membranes using a mesoscopic simulation model simple particle-based realization for flat support on to which lipids are adsorbed. show that nanometer roughness of affects membrane binding strength very little. then compare distributions pressure profiles free membranes. The surface localization proximal leaflet breaks symmetry seen in bilayer, we quantify entropic penalty increased lateral compression modulus.