Genes related with alzheimer's disease: a comparison of evolutionary search, statistical and integer programming approaches

作者: Pablo Moscato , Regina Berretta , Mou’ath Hourani , Alexandre Mendes , Carlos Cotta

DOI: 10.1007/978-3-540-32003-6_9

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摘要: Three different methodologies have been applied to microarray data from brains of Alzheimer diagnosed patients and healthy taken as control. A clear pattern differential gene expression results which can be regarded a molecular signature the disease. The show complementarity methodologies, suggesting that unified approach may help uncover complex genetic risk factors not currently discovered with single method. We also compare set genes in these patterns those already reported literature.

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