Targeting the p53/MDM2 Pathway for Cancer Therapy

Chène P, Howard Sf, Lane Dp, Picksley Sm, Böttger, Hochkeppel Hk, Garcia-Echeverria C, Böttger A, Identification of novel mdm2 binding peptides by phage display. Oncogene. ,vol. 13, pp. 2141- 2147 ,(1996)

E A Komarova, A V Gudkov, Suppression of p53: a New Approach to Overcome Side Effects of Antitumor Therapy Biochemistry. ,vol. 65, pp. 41- 48 ,(2000)

Rishu Takimoto, Wenge Wang, David T. Dicker, Farzan Rastinejad, Joseph Lyssikatos, Wafik S. El-Deiry, The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein. Cancer Biology & Therapy. ,vol. 1, pp. 47- 55 ,(2002) , 10.4161/CBT.1.1.41

Wafik S. El-Deiry, Regulation of p53 downstream genes. Seminars in Cancer Biology. ,vol. 8, pp. 345- 357 ,(1998) , 10.1006/SCBI.1998.0097

Karen H Vousden, p53: death star. Cell. ,vol. 103, pp. 691- 694 ,(2000) , 10.1016/S0092-8674(00)00171-9

Lihong Chen, Wenge Lu, Sudhir Agrawal, Wenqiang Zhou, Ruiwen Zhang, Jiandong Chen, Ubiquitous induction of p53 in tumor cells by antisense inhibition of MDM2 expression. Molecular Medicine. ,vol. 5, pp. 21- 34 ,(1999) , 10.1007/BF03402136

Erica Golemis, PROTEIN-PROTEIN INTERACTIONS: a molecular cloning manual : Cold Spring Harbor Laboratory Press. ,(2017)

Charles W. Stephen, David P. Lane, Mutant conformation of p53 Journal of Molecular Biology. ,vol. 225, pp. 577- 583 ,(1992) , 10.1016/0022-2836(92)90386-X

Koji Itahana, Goberdhan Dimri, Judith Campisi, Regulation of cellular senescence by p53 FEBS Journal. ,vol. 268, pp. 2784- 2791 ,(2001) , 10.1046/J.1432-1327.2001.02228.X

Tamar Juven-Gershon, Moshe Oren, Mdm2: The Ups and Downs Molecular Medicine. ,vol. 5, pp. 71- 83 ,(1999) , 10.1007/BF03402141