Containment and competition: Transgenic animals in the One Health agenda

摘要: The development of the One World, Health agenda coincides in time with appearance a different model for management human-animal relations: genetic manipulation animal species order to curtail their ability as carriers human pathogens. In this paper we examine two examples emergent transgenic approach disease control: chickens incapable shedding avian flu viruses, and creation mosquitoes refractory dengue or malaria infection. Our analysis elaborates three distinctions between its counterpoint. first concerns conceptualization outbreaks forms surveillance that support control efforts. second addresses nature interspecies interface, relative role humans animals preventing pathogen transmission. third axis comparison considers proprietary dimensions implications assumed public health ethos programs. We argue fundamental difference these approaches infectious can be summarized one strategies containment competition. While programs seek establish an equilibrium interface contain circulation pathogens across species, deliberately trigger new ecological dynamic by introducing novel varieties designed out-compete pathogen-carrying hosts vectors. other words, while policies focus on measures inter-species containment, derive prophylactic benefit from provoking cycles intra-species competition GM wild-type counterparts. coexistence divergent protection strategies, suggest, helps elucidate enduring tensions about how should relate to, appraise, intervene habitats.