Usefulness of MIB1 monoclonal antibody in assessing the proliferative index in human bladder carcinoma: comparison with Ki-67 antibody
作者： C. MAZEROLLES , P. RISHMANN , D. CHOPIN , Z. POPOPIN , B. MALAVAUD
DOI: 10.1111/J.1365-2559.1994.TB01375.X
关键词:
摘要: The reactivity of MIB1 antibody on routinely processed paraffin sections was compared with that Ki-67 frozen 80 transitional cell carcinomas the bladder. percentage labelled cells expressed as labelling index. indices were higher than those but for each case two values strongly correlated (r= 0.91). and also to tumour grade stage (P 0.001). determined after both formaldehyde ethanol based Bouin's fluid fixatives did not show any significant difference. staining microwave oven heating tissue is a simple technique assessing proliferative fraction bladder tumours fixed material. use permits retrospective studies should determine whether proliferation index in carcinoma has same prognostic value demonstrated other types neoplasms.
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