Arrhenius activation energy of damage to catalase during spray-drying.
作者： Joachim Schaefer , Geoffrey Lee
DOI: 10.1016/J.IJPHARM.2015.04.078
关键词:
摘要: The inactivation of catalase during spray-drying over a range outlet gas temperatures could be closely represented by the Arrhenius equation. From this an activation energy for damage to calculated. close fit suggests that thermally-induced part complex drying and particle-formation processes takes place at constant temperature. These are rapid compared with residence time powder in collecting vessel cyclone where dried is exposed temperature equal approximately A lower after spray ultrasonic nozzle was found than 2-fluid under otherwise identical conditions. It feasible when mounted lid dryer heats up toward inlet much more air-cooled nozzle. Calculation also showed how stabilizing efficacy trehalose mannitol on varies strength across examined.
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