摘要: This article provides information on the clinical development of skin reactions after cryosurgery/cryotherapy and indications, complications contraindications cryosurgery. Successful cryosurgery requires rapid freezing slow thawing, minimum tissue temperature -25 to -60℃ and, in malignant lesions, repetition freeze-thaw cycle. Frozen reacts with peripheral erythema immediately followed by edema, bulla formation, exudation mumification. Lesions usually heal a fine atrophic scar approximately 4 weeks. Nowadays, is considered treatment choice hypertrophic scars keloids, granuloma annulare, small capillary infantile hemangioma isolated actinic keratoses. It also valuable alternative therapy for various other diseases, including common warts, solar lentigo, superficial basal cell carcinoma Kaposi's sarcoma. Cryosurgery safe regimen relatively few adverse effects contraindications. Pain during and/or shortly treatment, formation local edema are major temporary effects; lesional hypopigmentation hyperpigmentation most long-term complication.