Recombinant bacterium to decrease tumor growth
作者： Roy Curtiss , Wei Kong
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摘要: A recombinant bacterium capable of reducing tumor growth is provided, wherein said of: a. increased expression a nucleic acid encoding chemoreceptor that directs chemotaxis towards tumors, b. accumulation in quiescent tumor, c. hyper-invasion d. reduced fitness normal tissue, e. enhanced stimulation the host innate immune responses, f. delivering specific DNA vaccine vector to cell, and g. bacterium-induced programmed cell death.
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