Detection of HPV genotypes in cervical lesions by the HPV DNA Chip and sequencing

摘要: Objective. A newly introduced HPV detection technique in cervical lesion, the DNA Chip test, contains 24 probes and has advantage of being able to detect types at once. We performed sequencing compared results with that for evaluation accuracy test. Methods. The was samples 282 patients, where specific type had been shown sixteen cases multiple found test were included cases. also HPV-other 95 positive HPV-PCR, but not found. Results. In 257 (91.1%) cases, agreement Chip. 16 (5.7%), different from But, 9 absent interpretation impossible nine (3.2%). showed 94 (98.9%) type, HPV-81 (20.0%), HPV-62 (14.7%), HPV-84 (13.7%), HPV-61 (13.7%) frequently detected. Conclusion. is an accurate method detecting genotypes.