Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers

作者: Isaac B Hilton , Anthony M D'Ippolito , Christopher M Vockley , Pratiksha I Thakore , Gregory E Crawford

DOI: 10.1038/NBT.3199

关键词:

摘要: … , has not yet been extensively applied to epigenome editing. … would directly modulate the epigenome and activate nearby … control of the epigenome and downstream gene expression. …

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