The experience of adults with sickle cell disease and their HLA-matched adult sibling donors after allogeneic hematopoietic stem cell transplantation.

摘要: Aim To provide a rich description and in-depth understanding of the recipient-donor allogeneic hematopoietic stem cell transplantation experience. Background A transplant has high likelihood improving symptoms sickle disease in adults. While studies have reported experiences recipients donors with haematological malignancies, no published reports examined experience both adult their donors. Design Exploratory qualitative descriptive analysis. Methods We conducted individual interviews 13 (eight males, five females) representing dyads one triad from Midwest centre between August 2017-February 2018. Interviews were digitally audio-recorded, transcribed verbatim analysed using conventional content Findings Five themes identified: downward spiral second chance; getting monster off my back; difficult manageable; it was worth it; relating to healthcare team. Conclusions The results insights into complex nature perspectives Impact Health provider awareness can contribute family-centred care that supports health quality life for This promotes clinical improved communications by taking account knowledge, values informed preferences contributes decision-making care. Future research assess family support choice potential candidates.