A Growth-Based Framework for Leaf Shape Development and Diversity.
作者： Daniel Kierzkowski , Adam Runions , Francesco Vuolo , Sören Strauss , Rena Lymbouridou
DOI: 10.1016/J.CELL.2019.05.011
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摘要: Summary How do genes modify cellular growth to create morphological diversity? We study this problem in two related plants with differently shaped leaves: Arabidopsis thaliana (simple leaf shape) and Cardamine hirsuta (complex shape leaflets). use live imaging, modeling, genetics deconstruct these organ-level differences into their cell-level constituents: amount, direction, differentiation. show that depends on the interplay of modes: a conserved organ-wide growth mode reflects differentiation; local, directional involves patterning foci along leaf edge. Shape diversity results from distinct effects homeobox on SHOOTMERISTEMLESS broadens organ-wide relative edge-patterning, enabling leaflet emergence, while REDUCED COMPLEXITY inhibits locally around emerging leaflets, accentuating created by patterning. demonstrate predictivity our findings reconstructing key features C. hirsuta morphology A. thaliana. Video Abstract Download : video (99MB)
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