AAS, growth hormone, and insulin abuse: psychological and neuroendocrine effects

作者: Michael R Graham , Peter Evans , Bruce Davies , Julien S Baker

DOI: 10.2147/TCRM.S2495

关键词:

摘要: The nontherapeutic use of prescription medicines by individuals involved in sport is increasing. Anabolic-androgenic steroids (AAS) are the most widely abused drug. Much our knowledge psychological and physiological effects human growth hormone (hGH) insulin has been learned from defi ciency states. As a consequence Internet revolution, previously unobtainable expensive designer drugs, particularly recombinant (rhGH) insulin, have become freely available at ridiculously discounted prices countries such as China being abused. These drugs various medical personnel must aware that medicine abuse appears to be used not only for performance cosmetic reasons, but pre-morbidity.

参考文章(101)
K. E. Yarasheski, J. J. Zachweija, T. J. Angelopoulos, D. M. Bier, Short-term growth hormone treatment does not increase muscle protein synthesis in experienced weight lifters Journal of Applied Physiology. ,vol. 74, pp. 3073- 3076 ,(1993) , 10.1152/JAPPL.1993.74.6.3073
Shlomo Melmed, Medical progress: Acromegaly. The New England Journal of Medicine. ,vol. 355, pp. 2558- 2573 ,(2006) , 10.1056/NEJMRA062453
LA Gonder-Frederick, DJ Cox, WL Clarke, The Emotional, Social, and Behavioral Implications of Insulin-Induced Hypoglycemia. Seminars in Clinical Neuropsychiatry. ,vol. 2, pp. 57- 65 ,(1997) , 10.1053/SCNP00200057
S H L Thomas, M H Wisher, D Brandenburg, P H Sönksen, Insulin action on adipocytes. Evidence that the anti-lipolytic and lipogenic effects of insulin are mediated by the same receptor. Biochemical Journal. ,vol. 184, pp. 355- 360 ,(1979) , 10.1042/BJ1840355
David R Mottram, Drugs in Sport ,(1988)
E. M Cassidy, D J O'Halloran, S. Barry, Insulin as a substance of misuse in a patient with insulin dependent diabetes mellitus BMJ. ,vol. 319, pp. 1417- 1418 ,(1999) , 10.1136/BMJ.319.7222.1417
D. A. Fryburg, R. A. Gelfand, E. J. Barrett, Growth hormone acutely stimulates forearm muscle protein synthesis in normal humans American Journal of Physiology-endocrinology and Metabolism. ,vol. 260, ,(1991) , 10.1152/AJPENDO.1991.260.3.E499
K. E. Yarasheski, J. J. Zachwieja, J. A. Campbell, D. M. Bier, Effect of growth hormone and resistance exercise on muscle growth and strength in older men American Journal of Physiology-endocrinology and Metabolism. ,vol. 268, ,(1995) , 10.1152/AJPENDO.1995.268.2.E268
D. M. Crist, G. T. Peake, P. A. Egan, D. L. Waters, Body composition response to exogenous GH during training in highly conditioned adults Journal of Applied Physiology. ,vol. 65, pp. 579- 584 ,(1988) , 10.1152/JAPPL.1988.65.2.579
Roger D Weiss, Shelly F Greenfield, Lisa M Najavits, Jose A Soto, Dana Wyner, Mauricio Tohen, Margaret L Griffin, None, Medication Compliance Among Patients With Bipolar Disorder and Substance Use Disorder The Journal of Clinical Psychiatry. ,vol. 59, pp. 172- 174 ,(1998) , 10.4088/JCP.V59N0405