作者: Jun'ichi Kobayashi , Masami Ishibashi
DOI: 10.1016/S0099-9598(08)60105-4
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摘要: Publisher Summary This chapter discusses that marine alkaloids exhibit a variety of the biological activities and have therefore been great importance in many fields sciences. All nitrogen-containing secondary metabolites are considered as “alkaloids.” As recognition primary separate from ones is, cases, still obscure organisms, selection compounds may be arbitrary depends on interest reviewers to some extent. Many terpenoids steroids, particularly those possessing isocyanide, isothiocyanate, formamide functionalities, discovered organism. Tetrodotoxin (TTX, 1) is one best known toxins exhibits potent neurotoxicity by specifically blocking sodium channels excitable cell membranes. The etiology TTX has an interesting topic because wide distribution toxin among genetically unrelated animals remarkable regional well individual variations contents. source demonstrated bacteria, since its analogs were detected culture broth bacteria identified species Alteromonas, Vibrio, Psuedomonas had isolated red alga genus Janiu, xanthid crab, skin pufferfish.