Reduction in Tumor Burden Allowing Partial Nephrectomy following Preoperative Chemotherapy in Biopsy Proved Wilms Tumor

作者: Gordon A. McLorie , Patrick H. McKenna , Mark Greenberg , Paul Babyn , Paul Thorner

DOI: 10.1016/S0022-5347(17)37839-4

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摘要: AbstractDuring the last 6 years a treatment protocol of radiographic staging along with percutaneous biopsy to establish histological diagnosis has been used in 37 patients Wilms tumor. Combination chemotherapy was given for 4 weeks before definitive surgical resection. In 9 tumor shrinkage sufficient permit preservation portion affected kidney(s). stage V disease partial nephrectomy accomplished 5 patients. additional unilateral downstaging also allowed nephrectomy. The radiological and changes that this limited surgery are analyzed compared.

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