作者: S.F. Cotmore , P. Tattersall
DOI: 10.1016/B978-0-12-801238-3.02641-6
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摘要: The Parvoviridae comprise a family of small, isometric, non-enveloped viruses that contain compact linear single-stranded DNA genome around 5 kilobases. They all encode an endonuclease/helicase cooperates with host cell synthetic and damage machinery to replicate viral genomes by rolling-hairpin mechanism. Progeny are packaged vectorially into rugged, preassembled protein capsids the helicase, mature virions delivered intact infected nuclei where they ultimately eject their DNA. divided two subfamilies: Parvovirinae , which infect vertebrate hosts, Densovirinae invertebrates.