Supply Chain Optimization of Blood Products

作者: Serkan Gunpinar

DOI:

关键词:

摘要: Major challenges in the management of blood supply chain are related to the shortage and wastage of the blood products. Given the perishability characteristics of blood which can be stored up to a limited number of days, if hospitals and blood centers keep an excessive number of blood units on inventory, wastages may occur. On the other hand, if sufficient number of blood units are not stored on inventory, shortages of this resource may cause the cancellations of important activities and increase the fatality rates at hospitals. Three mathematical models have been developed with the goal to improve the efficiency of blood related activities at blood centers and hospitals. The first model uses an integer programming (IP) approach to identify the optimal order levels that minimizes the total cost, shortage and wastage levels of blood products at a hospital within a specified planning horizon. The IP model explicitly considers the age of blood inventory, uncertain demand, the demand for two types of patients and crossmatch-to-transfusion ratio. The second model formulates the different shortage and inventory distribution strategies of a blood center supplying blood products to multiple hospitals. The third model develops a vehicle routing problem for blood centers to minimize the daily distance travelled by bloodmobiles during the blood collection process. Optimal routing for each bloodmobiles is identified using CPLEX solver, branch \& bound and column generation algorithms and their solution times are compared.

参考文章(27)
L. Sinem Sarul, Eyup Cetin, A Blood Bank Location Model: A Multiobjective Approach European Journal of Pure and Applied Mathematics. ,vol. 2, pp. 112- 124 ,(2009)
Güvenç Şahin, Haldun Süral, Sedef Meral, None, Locational analysis for regionalization of Turkish Red Crescent blood services Computers & Operations Research. ,vol. 34, pp. 692- 704 ,(2007) , 10.1016/J.COR.2005.03.020
Parviz Ghandforoush, Tarun K. Sen, A DSS to manage platelet production supply chain for regional blood centers decision support systems. ,vol. 50, pp. 32- 42 ,(2010) , 10.1016/J.DSS.2010.06.005
Vera Hemmelmayr, Karl F. Doerner, Richard F. Hartl, Martin W.P. Savelsbergh, Vendor managed inventory for environments with stochastic product usage European Journal of Operational Research. ,vol. 202, pp. 686- 695 ,(2010) , 10.1016/J.EJOR.2009.06.003
Alain Chabrier, Vehicle Routing Problem with elementary shortest path based column generation Computers & Operations Research. ,vol. 33, pp. 2972- 2990 ,(2006) , 10.1016/J.COR.2005.02.029
Edgar Alfonso, Xiaolan Xie, Vincent Augusto, Olivier Garraud, Modeling and simulation of blood collection systems Health Care Management Science. ,vol. 15, pp. 63- 78 ,(2012) , 10.1007/S10729-011-9181-8
Gregory P. Prastacos, Blood Inventory Management: An Overview of Theory and Practice Management Science. ,vol. 30, pp. 777- 800 ,(1984) , 10.1287/MNSC.30.7.777
M. Mourgaya, F. Vanderbeck, Column generation based heuristic for tactical planning in multi-period vehicle routing European Journal of Operational Research. ,vol. 183, pp. 1028- 1041 ,(2007) , 10.1016/J.EJOR.2006.02.030
HO Olawumi, BO Bolaji, Blood utilization in elective surgical procedures in Ilorin Tropical Journal of Health Sciences. ,vol. 13, pp. 15- 17 ,(2006) , 10.4314/TJHC.V13I1.36702
Magali J. Fontaine, Yenho T. Chung, William M. Rogers, Harry D. Sussmann, Peter Quach, Susan A. Galel, Lawrence T. Goodnough, Feryal Erhun, Improving platelet supply chains through collaborations between blood centers and transfusion services Transfusion. ,vol. 49, pp. 2040- 2047 ,(2009) , 10.1111/J.1537-2995.2009.02236.X