Recovery from ischemic stroke: a translational research perspective for neurology

摘要: Ischemic stroke is the most frequent neurological disease, characterized by an age-related incidence and chronic disability in majority of patients. A great challenge acute to predict degree which a patient will eventually recover. Magnetic resonance imaging has revealed that treatment-induced reperfusion limits extent ischemic brain damage, thereby enabling rapid profound recovery. Nevertheless, patients may retain deficits motor, sensory or cognitive functions due residual lesion. Functional neuroimaging transcranial magnetic stimulation have shown recovery associated with abnormal activation perilesional vicinity areas remote from This likely related altered functional properties morphological changes both cerebral hemispheres. Recent neurorehabilitative strategies, including forced use, mental imagery peripheral nerve cortex stimulation, aim at modulating these networks. Accordingly, ...