Clinical features and mortality-related factors of extensive burns among young adults: the Kunshan disaster experience

作者: Ying-Zi Huang , Guo-Zhong Lu , Hong-Sheng Zhao , Li-Jun Liu , Jun Jin

DOI: 10.21037/ATM-20-288

关键词:

摘要: Background The aim of the study was to identify clinical features and factors associated with burn induced mortality among young adults after exposure indoor explosion fire. Methods This is an observational which included patients who were admitted eighteen ICUs a fire disaster. Epidemiologic characteristics, as well therapy recorded. primary outcome 90-day mortality. mortality-related also analyzed. Results There 167 enrolled in study, median age 38 years, 62 (37.1%) died within 90 days. Seventy-one percent had size ≥90% TBSA, 73.7% full-thickness area above 50% TBSA. survivors lower Baux scores, received earlier escharectomy autologous skin grafts. rates (LA50s) for 95.8% 88.6% respectively. multivariate analysis showed that over TBSA residual burned surface (RBSA)/TBSA at 28 days strong predictors (odds ratio 2.55; 95% CI, 1.01 6.44, P=0.047; odds 1.07; 1.04 1.09, P<0.001). ROC curve-based cut-off values RBSA/TBSA predicting 62.5%. Conclusions Burn main risk poor extensive burns. Earlier grafts may improve outcomes.

参考文章(25)
Tina L. Palmieri, Fred Molitor, Grace Chan, Elizabeth Phelan, Brian J. Shier, Soman Sen, David G. Greenhalgh, Long-term functional outcomes in the elderly after burn injury. Journal of Burn Care & Research. ,vol. 33, pp. 497- 503 ,(2012) , 10.1097/BCR.0B013E31825AEAAC
W. C. Quinby, J. F. Burke, C. C. Bondoc, Primary excision and immediate wound closure Intensive Care Medicine. ,vol. 7, pp. 71- 76 ,(1981) , 10.1007/BF01687263
Juan P. Barret, David N. Herndon, Effects of burn wound excision on bacterial colonization and invasion. Plastic and Reconstructive Surgery. ,vol. 111, pp. 744- 750 ,(2003) , 10.1097/01.PRS.0000041445.76730.23
Yu Wang, Hong-Tai Tang, Zhao-Fan Xia, Shi-Hui Zhu, Bing Ma, Wei Wei, Yu Sun, Kai-Yang Lv, Factors affecting survival in adult patients with massive burns Burns. ,vol. 36, pp. 57- 64 ,(2010) , 10.1016/J.BURNS.2009.04.014
Annika Reintam Blaser, Manu L. N. G. Malbrain, Joel Starkopf, Sonja Fruhwald, Stephan M. Jakob, Jan De Waele, Jan-Peter Braun, Martijn Poeze, Claudia Spies, Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal Problems Intensive Care Medicine. ,vol. 38, pp. 384- 394 ,(2012) , 10.1007/S00134-011-2459-Y
DAVID N. HERNDON, ROBERT E. BARROW, RANDI L. RUTAN, THOMAS C. RUTAN, MANU H. DESAI, SALLY ABSTON, A comparison of conservative versus early excision. Therapies in severely burned patients. Annals of Surgery. ,vol. 209, pp. 547- 553 ,(1989) , 10.1097/00000658-198905000-00006
Jennifer D. Paratz, Kellie Stockton, Elizabeth D. Paratz, Stijn Blot, Michael Muller, Jeffrey Lipman, Robert J. Boots, Burn resuscitation--hourly urine output versus alternative endpoints: a systematic review. Shock. ,vol. 42, pp. 295- 306 ,(2014) , 10.1097/SHK.0000000000000204