Abnormal neuronal network in anorexia nervosa studied with I-123-IMP SPECT

作者: Akihiro Takano , Tohru Shiga , Nobuki Kitagawa , Tsukasa Koyama , Chietsugu Katoh

DOI: 10.1016/S0925-4927(01)00093-2

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摘要: Single photon emission computed tomography was used to study 14 female patients with anorexia nervosa and 8 normal comparison subjects. Automatic voxel-based analysis of the images carried out using statistical parametric mapping (SPM) software. Statistics across entire brain were displayed as Z scores (threshold: P<0.05). Compared subjects, anorectic characterized by hypoperfusion in medial prefrontal cortex anterior cingulate gyrus, hyperperfusion thalamus amygdala-hippocampus complex. These results suggest that a dysfunction neuronal circuitry may be related nervosa.

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