[Steroid-responsive nephrotic syndrome in IgA nephropathy].

摘要: A 46-year-old male, smoker of half a packet day and an alcohol intake 80 grams day, with unremarkable medical history, was referred to our service in the year 1988 for study nephrotic syndrome. He presented normal renal function, without either microhematuria nor hypertension. In blood analysis albuminemia 10 g/l proteinuria 22 g/d observed. first biopsy carried out which indicated minimal change disease. Steroid treatment started, as result syndrome disappeared normalized. Later he had 4 new outbreaks, all them steroid-responsive. 1992 second performed after fourth outbreak presence mild failure, that this time IgA nephropathy. tried again, cyclophosphamide added try reduce steroid doses. This normalization function decrease 2 g/d. The patient remained stable until 1996 when fifth occurred, again failure range. Therefore third performed, confirmed nephropathy, but now signs histological progression Following this, five outbreaks 3 years, steroid-responsive, although normalization. 2000, at his tenth it decided add cyclosporine treatment, achieving stability patient, further now, 1.6 C. creat. 59 ml/min.