作者: G. Donatini , A. Beaulieu , M. Castagnet , J.-L. Kraimps , P. Levillain
DOI: 10.1007/S40618-015-0356-X
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摘要: Introduction Hurthle cell tumors (HCTs) are rare thyroid neoplasia. To date, capsular and/or vascular invasion the only findings predicting malignancy. Recently, mutation of 19p13, encoding two proteins involved in proliferation and apoptosis (GRIM-19 p19), has been described. The aim our study is to evaluate cellular index (Ki67), GRIM-19 p19 expression as diagnostic markers malignancy HCT.