Thyroid Hürthle cell tumors: research of potential markers of malignancy.

作者: G. Donatini , A. Beaulieu , M. Castagnet , J.-L. Kraimps , P. Levillain

DOI: 10.1007/S40618-015-0356-X

关键词:

摘要: Introduction Hurthle cell tumors (HCTs) are rare thyroid neoplasia. To date, capsular and/or vascular invasion the only findings predicting malignancy. Recently, mutation of 19p13, encoding two proteins involved in proliferation and apoptosis (GRIM-19 p19), has been described. The aim our study is to evaluate cellular index (Ki67), GRIM-19 p19 expression as diagnostic markers malignancy HCT.

参考文章(34)
Ronald A. DeLellis, Pathology and genetics of tumours of endocrine organs IARC Press. ,(2004)
Paolo Goffredo, Sanziana A. Roman, Julie A. Sosa, Hurthle cell carcinoma: a population-level analysis of 3311 patients. Cancer. ,vol. 119, pp. 504- 511 ,(2013) , 10.1002/CNCR.27770
M Appetecchia, G Spriano, A Barnabei, E Ferretti, R Baldelli, A Procaccini, Hurthle cell tumours of the thyroid. Personal experience and review of the literature. Acta Otorhinolaryngologica Italica. ,vol. 29, pp. 305- 311 ,(2009)
O Nilsson, L E Tisell, A Oden, A Muth, G Altiparmak, J Mõlne, H Ahlman, The Ki67 index a prognostic marker in medullary thyroid carcinoma British Journal of Cancer. ,vol. 89, pp. 2093- 2097 ,(2003) , 10.1038/SJ.BJC.6601453
Kwang Hwi Lee, Jung Hee Shin, Eun Sook Ko, Soo Yeon Hahn, Jee Soo Kim, Jung-Han Kim, Young Lyun Oh, Predictive factors of malignancy in patients with cytologically suspicious for Hurthle cell neoplasm of thyroid nodules International Journal of Surgery. ,vol. 11, pp. 898- 902 ,(2013) , 10.1016/J.IJSU.2013.07.010
A Fusco, G Viglietto, M Santoro, Point mutation in GRIM-19: a new genetic lesion in Hurthle cell thyroid carcinomas. British Journal of Cancer. ,vol. 92, pp. 1817- 1818 ,(2005) , 10.1038/SJ.BJC.6602556
Jon E. Angell, Daniel J. Lindner, Paul S. Shapiro, Edward R. Hofmann, Dhananjaya V. Kalvakolanu, Identification of GRIM-19, a Novel Cell Death-regulatory Gene Induced by the Interferon-β and Retinoic Acid Combination, Using a Genetic Approach Journal of Biological Chemistry. ,vol. 275, pp. 33416- 33426 ,(2000) , 10.1074/JBC.M003929200
Jahn M. Nesland, Manuel A. Sobrinho-simões, Ruth Holm, Maria Clara Sambade, Jan Vincents Johannessen, Hürthle-Cell Lesions of the Thyroid: A Combined Study Using Transmission Electron Microscopy, Scanning Electron Microscopy, and Immunocytochemistry Ultrastructural Pathology. ,vol. 8, pp. 269- 290 ,(1985) , 10.3109/01913128509141518
Adolfo Pisanu, Barbara Di Chiara, Isabella Reccia, Alessandro Uccheddu, Oncocytic Cell Tumors of the Thyroid: Factors Predicting Malignancy and Influencing Prognosis, Treatment Decisions, and Outcomes World Journal of Surgery. ,vol. 34, pp. 836- 843 ,(2010) , 10.1007/S00268-009-0357-Z