The role of dendritic cells in tissue-specific autoimmunity.

作者: Jacques Mbongue , Dequina Nicholas , Anthony Firek , William Langridge

DOI: 10.1155/2014/857143

关键词:

摘要: In this review, we explore the role of dendritic cell subsets in development tissue-specific autoimmune diseases. From increasing list subclasses, it is becoming clear that are only at beginning understanding these antigen presenting cells mediating autoimmunity. Emerging research areas for study involvement onset and inhibition autoimmunity presented. Further, compare tissue specific to systemic demonstrate how cell-based therapies may be broadly applicable both classes Continued will lead us closer clinical assessment novel immunosuppressive therapy reversal prevention Through description functions modulation autoimmunity, hope stimulate a greater appreciation play treatment

参考文章(164)
R. Tisch, B. Wang, Role of plasmacytoid dendritic cells in type 1 diabetes: Friend or foe? Diabetes. ,vol. 58, pp. 12- 13 ,(2009) , 10.2337/DB08-1341
Philip L. Cohen, Roberto Caricchio, Valsamma Abraham, Todd D. Camenisch, J. Charles Jennette, Robert A.S. Roubey, H. Shelton Earp, Glenn Matsushima, Elizabeth A. Reap, Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase. Journal of Experimental Medicine. ,vol. 196, pp. 135- 140 ,(2002) , 10.1084/JEM.20012094
Teunis B.H. Geijtenbeek, Sandra J. van Vliet, Anneke Engering, Bert A. 't Hart, Yvette van Kooyk, Self- and Nonself-Recognition by C-Type Lectins on Dendritic Cells Annual Review of Immunology. ,vol. 22, pp. 33- 54 ,(2004) , 10.1146/ANNUREV.IMMUNOL.22.012703.104558
Matthias Sieber, Ria Baumgrass, Novel inhibitors of the calcineurin/NFATc hub - alternatives to CsA and FK506? Cell Communication and Signaling. ,vol. 7, pp. 25- 25 ,(2009) , 10.1186/1478-811X-7-25
Bruno Kyewski, Ludger Klein, A CENTRAL ROLE FOR CENTRAL TOLERANCE Annual Review of Immunology. ,vol. 24, pp. 571- 606 ,(2006) , 10.1146/ANNUREV.IMMUNOL.23.021704.115601
Hiroshi T. Ichikawa, Lucas P. Williams, Benjamin M. Segal, Activation of APCs Through CD40 or Toll-Like Receptor 9 Overcomes Tolerance and Precipitates Autoimmune Disease The Journal of Immunology. ,vol. 169, pp. 2781- 2787 ,(2002) , 10.4049/JIMMUNOL.169.5.2781
Francesca Fallarino, Carmine Vacca, Ciriana Orabona, Maria L. Belladonna, Roberta Bianchi, Brendan Marshall, Derin B. Keskin, Andrew L. Mellor, Maria C. Fioretti, Ursula Grohmann, Paolo Puccetti, Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells International Immunology. ,vol. 14, pp. 65- 68 ,(2002) , 10.1093/INTIMM/14.1.65
Chris R. Kintner, John R. Shutter, Gisele A. Deblandre, Sheila Scully, William G. Richards, Wei Fan, Kevin L. Stark, Jan Kitajewski, Dll4, a novel Notch ligand expressed in arterial endothelium Genes & Development. ,vol. 14, pp. 1313- 1318 ,(2000) , 10.1101/GAD.14.11.1313
B L McRae, C L Vanderlugt, M C Dal Canto, S D Miller, Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis. Journal of Experimental Medicine. ,vol. 182, pp. 75- 85 ,(1995) , 10.1084/JEM.182.1.75