Mitochondrial network in the heart
作者： Qian Li , Lu-Yu Zhou , Gui-Feng Gao , Jian-Qin Jiao , Pei-Feng Li
DOI: 10.1007/S13238-012-2921-9
关键词:
摘要: Mitochondria are subcellular organelles that provide energy for the cell. They form a dynamic tubular network and play an important role in maintaining cell function integrity. Heart is powerful organ supplies motivation circulation, thereby requiring large amounts of energy. Thus, healthiness cardiomyocytes mitochondria necessary normal cardiac function. not only lie center apoptotic pathway, but also major source reactive oxygen species (ROS) generation. Mitochondrial morphological change includes fission fusion regulated by number proteins. In this review we discuss regulators mitochondrial fission/fusion their association with apoptosis, autophagy ROS production heart.
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