STEROID COMPOUNDS AS RORyt MODULATORS AND USES THEREOF

作者: Michael R. Krout , Nicolas Gabriel Albert Manel , Dan R. Littman , Jun R. Huh , Daniel A. Ryan

DOI:

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摘要: Steroid compounds are disclosed that have a formula represented by the following: and wherein m, n, t, u1, u2, v1, v2, R 1a , 1b 2a 2b 3a 3b 3c 3d and Y as described herein. The may be prepared pharmaceutical compositions, used for treatment or prevention of variety conditions in mammals including humans, way non-limiting example, inflammatory conditions, autoimmune disorders, cancer, graft-versus-host disease.

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