Thymus-derived inhibitor of lymphocyte proliferation. II. Tissue specificity in vitro and in vivo.

作者: E. O. Rijke , H. C. M. Lempers , R. E. Ballieux

DOI: 10.1111/J.1365-2184.1981.TB00508.X

关键词:

摘要: A thymus crude factor (TCF) isolated from bovine tissue has been tested for its effects on the proliferation of various murine cells. Specific inhibition in vitro found DNA synthesis T and B lymphocytes which appears not to be based cytotoxicity. Moreover, TCF, when administered mice, also interferes with lymphoid vivo. Our data are suggestive presence TCF an endogenous 'chalone-like' inhibitor cell

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