Evidence for distinct brain networks in the control of rule-based motor behavior

摘要: Guiding a reach when the spatial location of viewed target and hand movement are not congruent (i.e. decoupled) can rely on use explicit cognitive rules (strategic control) or implicit recalibration gaze limb position (sensorimotor recalibration). We previously demonstrated, in patient with optic ataxia (OA) having bilateral superior parietal lobule damage, an increased reliance strategic control performing decoupled (Granek et al. 2013). To understand fundamental mechanisms visuomotor more generally to test whether we could distinguish these two modes specifically, tested healthy participants cognitively-demanding dual task. Participants continuously counted backwards while simultaneously reaching towards horizontal (left right) diagonal (~top-left ~top-right) targets either veridical rotated (90°) cursor feedback. By increasing overall neural load selectively compromising potentially overlapping circuits responsible for control, complex task served as non-invasive means disrupt integration rule into motor action. Complementary our previous results observed patients OA, here led greater performance deficits during movements that required rule, implying selective disruption reaching. Our suggest distinct processing is different types reaching, since, considering current together, classes be differentiated depending type interference.