Prevention of Epileptic Seizures by Taurine

作者: Abdeslem El Idrissi , Jeffrey Messing , Jason Scalia , Ekkhart Trenkner

DOI: 10.1007/978-1-4615-0077-3_62

关键词:

摘要: Parenteral injection of kainic acid (KA), a glutamate receptor agonist, causes severe and stereotyped behavioral convulsions in mice is used as rodent model for human temporal lobe epilepsy. The goal this study to examine the potential anti-convulsive effects neuro-active amino taurine, mouse KA-induced limbic seizures.

参考文章(13)
Kinya Kuriyama, Tsuneichi Hashimoto, INTERRELATIONSHIP BETWEEN TAURINE AND GABA Advances in Experimental Medicine and Biology. ,vol. 442, pp. 329- 337 ,(1998) , 10.1007/978-1-4899-0117-0_41
Kimberly Goslin, Gary Banker, Culturing nerve cells MIT Press. ,(1998)
Abdeslem El Idrissi, Ekkhart Trenkner, Growth Factors and Taurine Protect against Excitotoxicity by Stabilizing Calcium Homeostasis and Energy Metabolism The Journal of Neuroscience. ,vol. 19, pp. 9459- 9468 ,(1999) , 10.1523/JNEUROSCI.19-21-09459.1999
Gregory L. Holmes, Yehezkel Ben-Ari, Seizures in the developing brain: perhaps not so benign after all. Neuron. ,vol. 21, pp. 1231- 1234 ,(1998) , 10.1016/S0896-6273(00)80642-X
B. Eppler, T. A. Patterson, W. Zhou, W. J. Millard, R. Dawson, Kainic acid (KA)-induced seizures in Sprague-Dawley rats and the effect of dietary taurine (TAU) supplementation or deficiency Amino Acids. ,vol. 16, pp. 133- 147 ,(1999) , 10.1007/BF01321532
Nuria del Olmo, Julián Bustamante, Rafael Martı́n del Rı́o, José M Solı́s, Taurine activates GABAA but not GABAB receptors in rat hippocampal CA1 area Brain Research. ,vol. 864, pp. 298- 307 ,(2000) , 10.1016/S0006-8993(00)02211-3
Dian-Shi Wang, Tian-Le Xu, Zhi-Ping Pang, Ji-Shuo Li, Norio Akaike, Taurine-activated chloride currents in the rat sacral dorsal commissural neurons. Brain Research. ,vol. 792, pp. 41- 47 ,(1998) , 10.1016/S0006-8993(98)00119-X
Yehezkel Ben-Ari, Excitatory actions of gaba during development: the nature of the nurture Nature Reviews Neuroscience. ,vol. 3, pp. 728- 739 ,(2002) , 10.1038/NRN920