Intracerebral administration of interleukin-12 (IL-12) and IL-18 modifies the course of mouse scrapie.
作者： Paolo Pasquali , Romolo Nonno , Maria Mandara , Michele Di Bari , Giovanni Ricci
关键词:
摘要: Background Prion diseases are characterised by a neurodegenerative pattern in which the function of immune system remains still elusive. In present study, we evaluate if an exogenous treatment with Interleukin-12 (IL-12) and IL-18, able to activate microglia, is affect scrapie pathogenesis.
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