The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development
作者： CJ Formstone , PFR Little , None
DOI: 10.1016/S0925-4773(01)00515-9
关键词:
摘要: We have isolated cDNAs for three members of a family seven-pass transmembrane cadherins in mouse (Celsr1, 2 and 3). These genes represent vertebrate homologues flamingo/starry night, recently identified as an essential component the Drosophila planar cell polarity pathway correct formation dendritic fields within peripheral nervous system. In this study, we show that each member Celsr exhibit distinct patterns expression range different tissues developing embryo. Celsr1 Celsr2 is observed during gastrulation Celsr3 transcripts, however, are found only at sites active neurogenesis.
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