Transfer matrix solution of the Wako-Sait\^o-Mu\~noz-Eaton model augmented by arbitrary short range interactions

摘要: The Wako-Sait{\^o}-Mu\~noz-Eaton (WSME) model, initially introduced in the theory of protein folding, has also been used modeling RNA folding and some epitaxial phenomena. advantage this model is that it admits exact solution general inhomogeneous case (Bruscolini Pelizzola, 2002) which facilitates study realistic systems. However, a shortcoming accounts only for interactions within continuous stretches native bonds or atomic chains while neglecting interstretch (interchain) interactions. But due to biopolymer (atomic chain) flexibility, monomers (atoms) separated by several non-native along sequence can become closely spaced. This produces their strong interaction. inclusion non-WSME into makes more improves its performance. In we add arbitrary finite range solve new means transfer matrix technique. We therefore exactly account proteomics are classified as medium- moderately long-range ones.