Suppression of the Estradiol Receptor System by Progesterone in the Oviduct and Uterus of the Cat

摘要: Four weeks or more after being spayed, cats were either left untreated treated with various regimens of estradiol (E2) and progesterone (P) in silastic implants. Oviducts uteri then removed examined for morphological changes as well the amount compartmentalization estrogen receptor. E2 treatment restored a full complement ciliated secretory cells to oviduct, subsequent P (with without continuous E2) an E2-restored oviduct produced atrophied epithelium equivalent that resulting from withdrawal. In uterus, priming did not lead E2-withdrawal symptoms but rather new stage differentiation characterized by altered increased activity. both organs caused dramatic elevations E2-receptor content nuclear cytoplasmic compartments. Also (in organs) reduced compartments levels present spayed cats. The degree suppression was similar induced Suppression system correlated suppressed function inthe growth activity uterus.