In-vitro tipranavir susceptibility of HIV-1 isolates with reduced susceptibility to other protease inhibitors.

作者: Nicole K.T. Back , Albert van Wijk , DaniMlle Remmerswaal , Marion van Monfort , Monique Nijhuis

DOI: 10.1097/00002030-200001070-00019

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参考文章(7)
Steve R. Turner, Joseph W. Strohbach, Ruben A. Tommasi, Paul A. Aristoff, Paul D. Johnson, Harvey I. Skulnick, Lester A. Dolak, Eric P. Seest, Paul K. Tomich, Michael J. Bohanon, Miao-Miao Horng, Janet C. Lynn, Kong-Teck Chong, Roger R. Hinshaw, Keith D. Watenpaugh, Musiri N. Janakiraman, Suvit Thaisrivongs, Tipranavir (PNU-140690): A Potent, Orally Bioavailable Nonpeptidic HIV Protease Inhibitor of the 5,6-Dihydro-4-hydroxy-2-pyrone Sulfonamide Class∇ Journal of Medicinal Chemistry. ,vol. 41, pp. 3467- 3476 ,(1998) , 10.1021/JM9802158
R Boom, C J Sol, M M Salimans, C L Jansen, P M Wertheim-van Dillen, J van der Noordaa, Rapid and simple method for purification of nucleic acids. Journal of Clinical Microbiology. ,vol. 28, pp. 495- 503 ,(1990) , 10.1128/JCM.28.3.495-503.1990
S M Poppe, D E Slade, K T Chong, R R Hinshaw, P J Pagano, M Markowitz, D D Ho, H Mo, R R Gorman, T J Dueweke, S Thaisrivongs, W G Tarpley, Antiviral activity of the dihydropyrone PNU-140690, a new nonpeptidic human immunodeficiency virus protease inhibitor. Antimicrobial Agents and Chemotherapy. ,vol. 41, pp. 1058- 1063 ,(1997) , 10.1128/AAC.41.5.1058
C A Boucher, W Keulen, T van Bommel, M Nijhuis, D de Jong, M D de Jong, P Schipper, N K Back, Human immunodeficiency virus type 1 drug susceptibility determination by using recombinant viruses generated from patient sera tested in a cell-killing assay. Antimicrobial Agents and Chemotherapy. ,vol. 40, pp. 2404- 2409 ,(1996) , 10.1128/AAC.40.10.2404
M. Nijhuis, C. A. B. Boucher, P. Schipper, T. Leitner, R. Schuurman, J. Albert, Stochastic processes strongly influence HIV-1 evolution during suboptimal protease-inhibitor therapy Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 14441- 14446 ,(1998) , 10.1073/PNAS.95.24.14441