Binding polypeptides with restricted diversity sequences

作者: Sara C. Birtalan , Frederic A. Fellouse , Sachdev S. Sidhu

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摘要: The invention provides variant CDRs comprising highly restricted amino acid sequence diversity. These polypeptides provide a flexible and simple source of diversity that can be used as for identifying novel antigen binding polypeptides. also these fusion to heterologous such at least portion phage or viral coat proteins, tags linkers. Libraries plurality are provided. In addition, methods compositions generating using libraries

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