Update of the Drug Resistance Mutations in HIV-1: December 2008
作者： Daniel R. Kuritzkes , Bonaventura Clotet , Huldrych F. Günthard , Douglas D. Richman , Victoria A. Johnson
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摘要: The International AIDS Society-USA (IAS-USA) Drug Resistance Mutations Group reviews new data on HIV-1 drug resistance that have been published or presented at recent scientific meetings to maintain a current list of mutations associated with antiretroviral resistance.This December 2008 version the IAS-USA figures updates those in this journal March/April (Johnson VA, Brun-Vezinet F, Clotet B, et al, Top HIV Med, 2008;16:62-68). compilation includes may contribute reduced virologic response drugs. It should not be assumed here is exhaustive. Drugs approved by US Food and Administration (US FDA) as well any drugs available expanded access programs are included listed alphabetical order class. designed for practitioners use identifying key viral making therapeutic decisions. Updates posted periodically www.iasusa.org. For more in-depth reading an extensive reference list, see panel recommendations testing (Hirsch MS, Gunthard HF, Schapiro JM, Clin Infect Dis, 2008:47:266-285).
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