Synthetic triple helix-forming compounds
作者： Barry I. Gold
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摘要: The present invention discloses novel monomeric compositions which are substituted quinoline- or quinazoline-based structures capable of hydrogen bonding specifically with interstrand purine-pyrimidine base pairs in a double-stranded Watson-Crick DNA molecule. Furthermore, the compounds being assembled specific sequences into oligomers binding sequence specificity to duplex via triple helix motif.
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