Sex determines cardiovascular hemodynamics in hypertension.
作者： P Krzesiński , A Stańczyk , G Gielerak , B Uziębło-Życzkowska , M Kurpaska
DOI: 10.1038/JHH.2014.134
关键词:
摘要: The aim of this study was to evaluate the influence sex on cardiovascular hemodynamics and heart remodeling in 144 patients with arterial hypertension that underwent: (1) echocardiography (that is, indices left ventricular diastolic function: e′, E/e′), (2) impedance cardiography systemic vascular resistance (SVR), total artery compliance (TAC) Heather index (HI)) (3) applanation tonometry (augmentation (AI), central systolic blood pressure (CSBP, CDBP), pulse (CPP)). Women, comparison men, revealed have: stiffer arteries—lower TAC (1.93±0.55 vs 2.16±0.59 ml per mm Hg; P=0.025), higher CSBP (128.7±14.9 123.4±13.2 mm Hg; P=0.036), CPP (39.9±9.5 33.8±9.0 mm Hg; P=0.0002), AI (31.5±8.7 17.5±12.7%; P<0.00001), SVR (1257.6±305.6 1091.2±240.7 dyn × s cm−5; P=0.002) performance—HI (16.3±4.3 11.7±3.2 Ohm s2; P<0.00001). In women CSBP, were more clearly associated filling (e′) (r=−0.39, r=−0.45, r=−0.44, P<0.01; respectively). These relations remarkably weaker men. Hypertensive characterized lower large compliance, pronounced augmentation distinctive association function. Sex differences function can impact individualized management hypertension.
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