Microporous polysaccharide hemospheres for management of laparoscopic trocar injury to the spleen.

摘要: Abstract Background Management of iatrogenic injuries during laparoscopy can be arduous. Recent advancements in surgical hemostatic agents have provided beneficial therapeutic alternatives. This project evaluates microporous polysaccharide hemospheres (MPH), with demonstrated efficiency achieving topical hemostasis, the setting intracorporeal laparoscopic splenic injury. Methods Four domestic female pigs were subjected to reproducible 12-mm and 5-mm trocar injuries. Each surgery was an identical transperitoneal hand-assisted procedure. Hemostasis, or no bleeding after treatment, achieved by measured dose applications MPH. Results The MPH successfully hemostasis for all except 1 case, where a lesion transected artery. mean time MPH, estimated blood loss 5- 165.3 ± 45.7 200.7 106.5 seconds, 1.3 .5 both, 12.0 4.6 17.7 9.1g, respectively. Conclusions represents powerful agent that complete