Zusammenfassung: immunologische Reaktionsabläufe bei malignen Erkrankungen
作者： V. Schirrmacher
DOI: 10.1007/978-3-642-79744-6_17
关键词:
摘要: Der vorliegende Beitrag behandelt neuere Erkenntnisse uber Immunreaktion gegenuber Tumoren. Dieses schliest die Identifizierung neuer tumorassoziierte Antigene sowie Regulation von Antitumorimmunreaktionen durch Zytokine, akzessorische Molekulen und Wachstumsfaktoren ein. TumorWirtsinteraktionen fuhren auch zur Generierung Tumor-ImmunescapeVarianten, ebenfalls diskutiert werden. Schlieslich werden Ansatze zu Immun- Gentherapien erlautert es wird kurz auf einige Probleme bei der Durchfuhrung klinischer Krebsimmuntherapiestudien eingegangen.
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