Nonlesions, Unusual Cell Types, and Postmortem Artifacts in the Central Nervous System of Domestic Animals

作者: P. Wohlsein , U. Deschl , W. Baumgärtner

DOI: 10.1177/0300985812450719

关键词:

摘要: In the central nervous system (CNS) of domestic animals, numerous specialized normal structures, unusual cell types, findings uncertain or no significance, artifacts, and various postmortem alterations can be observed. They may cause confusion for inexperienced pathologists those not in neuropathology, leading to misinterpretations wrong diagnoses. Alternatively, changes mask underlying neuropathological processes. "Specialized structures" comprising hippocampus circumventricular organs, including vascular organ lamina terminalis, subfornical organ, subcommissural pineal gland, median eminence/neurohypophyseal complex, choroid plexus, area postrema, are displayed. Unusual cerebellar external germinal cells, CNS progenitor Kolmer presented. addition, some newly recognized types as yet incompletely understood significance functionality, such synantocytes aldynoglia, introduced described. reactive astrocytes cats, chromatolysis, neuronal vacuolation, spheroids, spongiosis, satellitosis, melanosis, neuromelanin, lipofuscin, polyglucosan bodies, psammoma bodies represent incidental should confused with significant microscopic changes. Auto- heterolysis well handling histotechnological processing morphological CNS, vacuolization, conglutination, dark neurons, Buscaino freezing, shrinkage all which have differentiated from genuine lesions. Postmortem invasion micro-organisms intravital infections. Awareness these different their recognition a prerequisite identifying lesions help formulate professional etiological diagnosis.

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