Anti-DNA, anti-HBc correlations with RIA-detected HBeAg and anti-HBe in chronic HBsAg carriers.
作者： VíCtor M. Villarejos , Kirsten Andersen-Visoná , Jaime Serra C. , Gert G. Frösner , Friedrich Deinhardt
DOI: 10.1002/1096-9071(1980)5:4<265::AID-JMV1890050402>3.0.CO;2-N
关键词:
摘要: The interrelations of 1) antibody to hepatitis B core antigen (HBcAg)--anti-HBc; 2) single-stranded DNA-binding antibodies (anti-DNA); and 3) the e-antigen/antibody system--hepatitis e (HBeAg) (anti-HBe), were studied in 150 surface (HBsAg) carriers, 43 whom diagnostic liver biopsies had been performed. There was a good correlation between titers anti-HBc anti-DNA, regarded as indicators viral pathological activity, respectively, well levels these two presence HBeAg or anti-HBE detected by radio-immune assay (RIA). In general, HBeAg-positive carriers showed high anti-DNA titers, while positive for anti-HBe low both. These findings accord with histopathological results. three serologic parameters, anti-HBc, e-antigen/antibody, should together prove useful evaluation clinical status chronic HBsAg carriers.
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