NADH supplementation decreases pinacidil‐primed IK(ATP) in ventricular cardiomyocytes by increasing intracellular ATP
作者： Brigitte Pelzmann , Seth Hallström , Peter Schaffer , Petra Lang , Karl Nadlinger
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摘要: 1 The aim of this study was to investigate the effect nicotinamide-adenine dinucleotide (NADH) supplementation on metabolic condition isolated guinea-pig ventricular cardiomyocytes. pinacidil-primed ATP-dependent potassium current IK(ATP) used as an indicator subsarcolemmal ATP concentration and intracellular adenine nucleotide contents were measured. 2 Membrane currents studied using patch-clamp technique in whole-cell recording
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